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Wikenigma - an Encyclopedia of Unknowns Wikenigma - an Encyclopedia of the Unknown

Gabapentin

Gabapentin, sold under the brandnames Gralise, Gabarone, Fanatrex, Neurontin (and mmany others) was discovered in the 1970s, and was first used as a muscle relaxant and painkiller.

In the US alone, it currently has more than 40 million prescriptions per year.

It's used to treat Restless leg syndromeplugin-autotooltip__plain plugin-autotooltip_bigRestless leg syndrome

Restless legs syndrome, also known as Willis-Ekbom disease, is a common condition of the nervous system that causes an overwhelming and irresistible urge to move the legs. Estimates are that around 10% of people suffer from RLS at some stage in th…
, Parkinson's diseaseplugin-autotooltip__plain plugin-autotooltip_bigParkinson's disease

Also known as Parkinson disease, Parkinson's, idiopathic parkinsonism, primary parkinsonism, PD, or paralysis agitans - is a degenerative disorder of the central nervous system resulting from the death of dopamine-containing cells in the
and Epilepsyplugin-autotooltip__plain plugin-autotooltip_bigEpilepsy

"“Epilepsy is a chronic noncommunicable disease of the brain that affects around 50 million people worldwide. It is characterized by recurrent seizures, which are brief episodes of involuntary movement that may involve a part of the body (partial) or the enti…
(and many other conditions).

Its 'mechanism of action' - both as an anticonvulsant and as an analgesic - are unknown.

Further info Anaesthesia Volume 57, Issue 5


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