Fluoxetine is a Selective Serotonin Reuptake Inhibitor (SSRI) used in the treatment of and etc.. It's marketed under the trade names Prozac, Sarafem, Fontex and many others.
SSRIs are believed to act by inhibiting the re-uptake of hormone serotonin after being released in the brain synapses. The exact mechanism for their operation is unknown.
Quote from the prescribing information datasheet for Prozac™, from manufacturer Eli Lilly and Company.
“Although the exact mechanism of PROZAC is unknown, it is presumed to be linked to its inhibition of CNS neuronal uptake of serotonin”
In addition, the theory that manipulating serotonin levels may help in treatments is itself also unproven :
… there exists no rigorous corroboration of the serotonin theory, and a significant body of contradictory evidence.“
Source : PloS Medicine 2005 Serotonin and Depression: A Disconnect between the Advertisements and the Scientific Literature
Ideas for new topics, and suggested additions / corrections for old ones, are always welcome.
If you have skills or interests in a particular field, and have suggestions for Wikenigma, get in touch !
Or, if you'd like to become a regular contributor . . . request a login password. Registered users can edit the entire content of the site, and also create new pages.
( The 'Notes for contributors' section in the main menu has further information and guidelines etc.)
You are currently viewing an auto-translated version of Wikenigma
Please be aware that no automatic translation engines are 100% accurate, and so the auto-translated content will very probably feature errors and omissions.
Nevertheless, Wikenigma hopes that the translated content will help to attract a wider global audience.