Fluoxetine is a Selective Serotonin Reuptake Inhibitor (SSRI) used in the treatment of and etc.. It's marketed under the trade names Prozac™, Sarafem™, Fontex™ etc.
SSRIs are believed to act by inhibiting the reuptake of serotonin after being released in the brain synapses. The exact mechanism for their operation is unknown.
Quote from the prescribing information datasheet for Prozac™, from manufacturer Eli Lilly and Company.
“Although the exact mechanism of PROZAC is unknown, it is presumed to be linked to its inhibition of CNS neuronal uptake of serotonin”
Further, the theory that manipulating serotonin levels may help in treatments is also unproven. See : PloS Medicine 2005 Serotonin and Depression: A Disconnect between the Advertisements and the Scientific Literature
“…there exists no rigorous corroboration of the serotonin theory, and a significant body of contradictory evidence.”
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