When organic 'tissue' grows (either during embryonic development, post-natal growth, or tissue regeneration) there are two processes in operation which determine the final size of the tissue or organ. The first is the size of the cells themselves - which is governed by an as yet unknown process (see:) The second factor is the number of cells, in other words the number of times which cell division occurs. Together, these two processes are known as 'cell proliferation'.
Since it's known that in almost all cases 'tissue' and organs stop growing at some point, there must be a regulatory mechanism which 'tells' the tissue to stop growing.
That mechanism is as yet unknown.
“How cell proliferation is controlled during tissue growth to determine final tissue size is an open question in biology.”
Note: Understanding cell proliferation is of profound relevance in cancer research - where one of the major factors is the unconstrained proliferation of cancerous cells.
Also see :
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