Please register and log-in to create and edit pages

User Tools

    Please register and log-in to create and edit pages

Site Tools


Main Menu

Main menu
Click categories to expand

Other categories


A-Z listingplugin-autotooltip__plain plugin-autotooltip_bigA-Z listing

This is an alphabetical index of all content pages.


Also see

Importance Ratingsplugin-autotooltip__plain plugin-autotooltip_bigImportance ratings

In a departure from the usual Wiki format, Wikenigma assigns 'Importance Ratings' to some pages.

The idea is to separate articles which are considered (by the editors) to cover exceptionally important unknown issues from those which (although also u…

Newsplugin-autotooltip__plain plugin-autotooltip_bigNews

[ newest at the top ]

• Mar. 2021 : Many thanks to the The British Library, which has now begun permanently archiving the contents of Wikenigma.

• Jan. 2021 : A milestone of 600 unknown articles has been reached.

• Oct. 2020 : A milestone of 500 unknown article…

Contactsplugin-autotooltip__plain plugin-autotooltip_bigContacts

Use this form to send a message to Wikenigma . . . [ * note: all fields must be completed ]

Legalplugin-autotooltip__plain plugin-autotooltip_bigLegal

Content in general

Please note that in common with other publicly editable wikis, this website is not responsible for content posted by the public. Nevertheless, the ongoing editing process should be able to remove unsuitable content in a reasonable time. If you…

Donate/Sponsorplugin-autotooltip__plain plugin-autotooltip_bigDonate to Wikenigma . . .

The best way to donate is by adding new original content !

That can either be by contributing to an existing article, or by creating a new page with an as-yet-unlisted 'Known Unknown'.

Any registered user can create content.

Registerplugin-autotooltip__plain plugin-autotooltip_bigRegistration

At present, only registered users can create and edit articles.

If you'd like to register as a contributor, please request a password.

When filling in the form, make sure you supply a valid e-mail address, as the login password will be sent to that addre…


Wikenigma supports:


Utilities
rss / xml feed
sitemap file
A-Z listing (archived)plugin-autotooltip__plain plugin-autotooltip_bigA-Z listing (archived)

This is an older, partial A-Z listing intended for search engines only.

Last updated : March 2021

For an up-to-date list see A-Z listing in the Main Menu

'Abracadabra' etymology

Acamprosate

Acrocyanosis

Acupuncture

Attention-Deficit / Hype…

Wikenigma - an Encyclopaedia of Unknowns Wikenigma - an Encyclopaedia of the Unknown Science

Gastrointestinal weight-loss surgery

Gastrointestinal weight-loss surgery, also known as Gastric Bypass surgery refers to surgical processes in which the stomach is divided and reduced (usually by more than 90%), and then the small intestine is rearranged to connect to the new, smaller, stomach 'pouch'.

It's normally viewed as a 'last-resort' method to combat severe obesity. It's very effective at weight reduction. and has been found to reduce obesity-related mortality by around 40%.

Variants of the procedure are now performed in hundreds of thousands of patients, worldwide, each year.

Since its development in the last decades of the 20th century, it was initally assumed that its effectiveness was due to a simply 'mechanical' effect which prevented excess eating and lowered digestion rates. This is now known to be an oversimplified viewpoint.

The way in which gastrointestinal weight-loss surgery leads to such significant weight-loss is currently regarded as an unsolved medical problem.

Gastrointestinal weight-loss surgery (GIWLS) is currently the most effective treatment for severe obesity, with Roux-en-Y gastric bypass (RYGB) among the best of the available surgical options. Despite its widespread clinical use, the mechanisms by which RYGB induces its profound weight loss remain largely unknown. This procedure effects weight loss by altering the physiology of weight regulation and eating behavior rather than by simple mechanical restriction and/or malabsorption as previously thought.
Source: Obesity Journal (Silver Spring). 2009 Oct; 17(10): 1839–1847.

Also see : Appetite Regulationplugin-autotooltip__plain plugin-autotooltip_bigAppetite Regulation

Very extensive research, over many decades, has identified a number of biochemical routes that can influence appetite in humans.

For an overview, see: Mechanisms of Appetite Regulation

In particular, the so called 'hunger hormones' leptin and ghre…


    Share this page :

X

Dear reader : Do you have any suggestions for the site's content?

Ideas for new topics, and suggested additions / corrections for old ones, are always welcome.

If you have skills or interests in a particular field, and have suggestions for Wikenigma, get in touch !


Or, if you'd like to become a regular contributor . . . request a login password. Registered users can edit the entire content of the site, and also create new pages.

( The 'Notes for contributors' section in the main menu has further information and guidelines etc.)

Show another (random) page

DOKUWIKI IMPLEMENTATION DESIGN BY UNIV.ORG.UK APRIL 2021