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Wikenigma - an Encyclopaedia of Unknowns Wikenigma - an Encyclopaedia of the Unknown Science

Defibrillation

Since the 1960s, electrical heart defibrillators have been routinely used as a treatment for life-threatening cardiac dysrhythmias, especially ventricular fibrillation. The exact mechanism of action is yet to be determined, but is presumably linked to large-scale electrical depolarization of the heart muscle.

“The exact mechanism of defibrillation is not well understood. One theory is that successful defibrillation affects a critical mass of the heart, resulting in insufficient remaining heart muscle to continue the arrhythmia. Recent mathematical models of defibrillation are providing new insight into how cardiac tissue responds to a strong electrical shock.”
Source: Wikipedia

Note: This topic is one of a small group of man-made technical systems which are in routine use, but are poorly understood. Other examples include Lithium-ion batteriesplugin-autotooltip__plain plugin-autotooltip_bigLithium-ion batteries

"“Although lithium ion batteries are considered as system of choice for variety of mobile and stationary applications, fundamental knowledge is alarmingly required to uncover the underlying principles controlling the basic processes that determin…
and Neural Networksplugin-autotooltip__plain plugin-autotooltip_bigNeural Networks

"“Multilayer neural networks are among the most powerful models in machine learning, yet the fundamental reasons for this success defy mathematical understanding.” Source: Proceedings of the National Academy of Sciences 2018"

'Artificial Intelligen…


Also seeElectroconvulsive therapy (ECT)plugin-autotooltip__plain plugin-autotooltip_bigElectroconvulsive therapy (ECT)

Electroconvulsive therapy (ECT), formerly known as electroshock therapy, is a psychiatric treatment in which seizures are electrically induced in patients, By an unknown mechanism, they provide relief from severe mental disorders - espec…


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