User Tools

    To create and edit articles, please register and log-in

Main Menu : categories & index etc.

Main menu
Click categories to expand

A-Z listingplugin-autotooltip__plain plugin-autotooltip_bigA-Z listing

This is an alphabetical index of all content pages.

Other categories



Also see

Importance Ratings
Curator's rationale
AI Policy

Twitter feed 𝕏

Feeds + s.e.o. etc.
rss / xml feed
sitemap file
A-Z listing (archived)

Indexed under : Medicine / Drugs

Wikenigma - an Encyclopedia of Unknowns Wikenigma - an Encyclopedia of the Unknown


Ranolazine - sold under brand names Ranexa and others - is a prescription-only medication used to treat anginaplugin-autotooltip__plain plugin-autotooltip_bigMicrovascular angina

Microvascular angina ( previously known as Cardiac Syndrome X ) is a form of angina (chest pain) associated with insufficient blood flow to the heart (and some other organs/regions) but in patients who have normal coronary angiograms.

It was approved in the US in 2006, where it's now prescribed more than one million times per year.

Although it's known that Ranolazine inhibits persistent or late inward sodium current in the heart muscles, the exact mechanism of action is unknown.

Exact mechanism of antianginal action not fully elucidated; may involve the shifting of adenosine triphosphate (ATP) production away from fatty acid oxidation (i.e., partial inhibition of fatty acid oxidation) in favor of more oxygen-efficient glucose oxidation, especially when free fatty acid concentrations are elevated (e.g., during ischemia), leading to reduced oxygen demand and symptoms of ischemia without affecting cardiac work.

Source :

    Please share this page to help promote Wikenigma !

Dear reader : Do you have any suggestions for the site's content?

Ideas for new topics, and suggested additions / corrections for older ones, are always welcome.

If you have skills or interests in a particular field, and have suggestions for Wikenigma, get in touch !

Or, if you'd like to become a regular contributor . . . request a login password. Registered users can edit the entire content of the site, and also create new pages.

( The 'Notes for contributors' section in the main menu has further information and guidelines etc.)

Automatic Translation

You are currently viewing an auto-translated version of Wikenigma

Please be aware that no automatic translation engines are 100% accurate, and so the auto-translated content will very probably feature errors and omissions.

Nevertheless, Wikenigma hopes that the translated content will help to attract a wider global audience.

Show another (random) article

Further resources :