Modafinil (sold under the brand names Alertec, Alertex, Altasomil, Aspendos, Forcilin, Intensit, Mentix, Modafinil, Modafinilo, Modalert, Modanil, Modasomil, Modvigil, Modiodal, Modiwake, Movigil, Provigil, Resotyl, Stavigile, Vigia, Vigicer, Vigil, Vigimax, Wakelert and Zalux among others) was was originally developed in France by professor Michel Jouvet and Lafon Laboratories (1970s).
In many countries it is currently a prescription-only medication, and is used to treat sleepiness due to narcolepsy, shift work sleep disorder, or obstructive sleep apnea. There are ongoing clinical trials for its use in fatigue, cocaine addiction,, , seasonal affective disorder, bipolar depression, nicotine addiction, and .
It's also routinely used by the military to keep operatives awake for long periods - and (unofficially) by shift workers and students studying for exams etc etc.
Its mechanism(s) of action have been very widely researched, but as yet there is no official consensus on how it works. To the extent that it's been called 'a drug in search of a mechanism'.
See: Mechanisms of modafinil: A review of current research Neuropsychiatric Disease and Treatment. 2007 Jun; 3(3): 349–364.
Ideas for new topics, and suggested additions / corrections for old ones, are always welcome.
If you have skills or interests in a particular field, and have suggestions for Wikenigma, get in touch !
Or, if you'd like to become a regular contributor . . . request a login password. Registered users can edit the entire content of the site, and also create new pages.
( The 'Notes for contributors' section in the main menu has further information and guidelines etc.)
You are currently viewing an auto-translated version of Wikenigma
Please be aware that no automatic translation engines are 100% accurate, and so the auto-translated content will very probably feature errors and omissions.
Nevertheless, Wikenigma hopes that the translated content will help to attract a wider global audience.