Please register and log-in to create and edit pages

User Tools

    Please register and log-in to create and edit pages

Site Tools


Main Menu

Main menu
Click categories to expand


A-Z listingplugin-autotooltip__plain plugin-autotooltip_bigA-Z listing

This is an alphabetical index of all content pages.


Other categories

Utilities

Contacts
Register

Also see

Importance Ratings
News
Legal
Donate/Sponsor


Wikenigma supports:


Feeds etc
rss / xml feed
sitemap file
A-Z listing (archived)

Wikenigma - an Encyclopaedia of Unknowns Wikenigma - an Encyclopaedia of the Unknown Science

Isotretinoin

Isotretinoin (13-cis-retinoic acid) is a medication primarily used to treat severe acne. It's also occasionally used to help prevent certain skin cancers such as squamous-cell carcinoma, and (rarely) in the treatment of some other cancers. It's sold under various brand names, including : Accutane, Roaccutane, Rizuderm and more than 120 others.

While isotretinoin is currently the most effective agent for patients with moderate-to-severe acne, the drug’s potential to induce human congenital abnormalities, and its wide range of adverse side-effects, is driving research to find replacements. This is hampered because :

“Isotretinoin's exact mechanism of action is unknown, but several studies have shown that isotretinoin induces apoptosis (programmatic cell death) in various cells in the body.”
Source: Wikipedia

At pharmacologic doses, isotretinoin inhibits sebaceous gland function and keratinization, but as noted above, its precise mechanism of action is unknown. Several studies have shown that isotretinoin induces apoptosis (programmatic cell death) in various cells in the body.


    Share this page :

X

Dear reader : Do you have any suggestions for the site's content?

Ideas for new topics, and suggested additions / corrections for old ones, are always welcome.

If you have skills or interests in a particular field, and have suggestions for Wikenigma, get in touch !


Or, if you'd like to become a regular contributor . . . request a login password. Registered users can edit the entire content of the site, and also create new pages.

( The 'Notes for contributors' section in the main menu has further information and guidelines etc.)

Show another (random) page

DOKUWIKI IMPLEMENTATION DESIGN BY UNIV.ORG.UK JULY 2021