Random article ( of 1069 ) Latest updates

User Tools

Site Tools


content:medicine:drugs:gemfibrozil

Wikenigma - an Encyclopedia of Unknowns Wikenigma - an Encyclopedia of the Unknown

Gemfibrozil

Gemfibrozil - sold under brand name of Lopid, Jezil and others - is used to treat abnormal blood lipid levels. Currently around 4 million prescriptions per year in the US alone. Its mechanism of action is, to date, unknown.

The exact mechanism of action of gemfibrozil is unknown; however, several theories exist regarding the very low density lipoprotein (VLDL) effect; it can inhibit lipolysis and decrease subsequent hepatic fatty acid uptake as well as inhibit hepatic secretion of VLDL; together these actions decrease serum VLDL levels and increase HDL-cholesterol; the mechanism behind HDL elevation is currently unknown.

Source Wikipedia

Show another (random) article

Suggestions for corrections and ideas for articles are welcomed : Get in touch!


Further resources :