Uddanam nephropathy is a chronic kidney disease of unknown origin that's endemic in the region of Uddanam, Andhra Pradesh, India.

As of 2015, it was estimated that more than 4,500 people in the area had died from chronic kidney disease in the last ten years, and around 34,000 people had kidney diseases.

Like Mesoamerican nephropathyplugin-autotooltip__plain plugin-autotooltip_bigMesoamerican nephropathy

"An epidemic of chronic kidney disease of unknown origin has emerged in the last decade in Central America and has been named Mesoamerican nephropathy. This form of chronic kidney disease is present primarily in young male agricultural workers from communities along the Pacific coast, especially workers in the sugarcane fields. In general, these men have a history of manual labor under very hot conditions in agricultural fields.", it's suggested that the condition could be the result of exposure to toxic agro-chemicals, or dehydrating long work-hours in extreme heat.

Although the association of specific occupations with endemic nephropathy has highlighted the issue of environmental toxins and heat stress, the cause of Uddanam nephropathy is still an enigma.

Source : AKJD editorial, Volume 68, Issue 3,