HELLP syndrome is a life-threatening condition that can potentially complicate pregnancy. It is named for 3 features of the condition: Hemolysis, Elevated Liver enzyme levels, and Low Platelet levels. It typically occurs in the last 3 months of pregnancy (the third trimester) but can also start soon after delivery. A wide range of non-specific symptoms may be present in women with HELLP syndrome. Symptoms may include fatigue; malaise; fluid retention and excess weight gain; headache; nausea and vomiting; pain in the upper right or middle of the abdomen; blurry vision; and rarely, nosebleed or seizures.â
Source : US NIH, NCATS
It affects around 0.5 to 0.9% of all pregnancies, i.e. many millions per year. About 70% of the cases develop before delivery, the majority between the 27th and 37th gestational weeks; the remainder within 48 hours after delivery.
The cause(s) of HELLP are currently unknown. though it's markedly more common in women who have pre-eclampsia or pregnancy induced hypertension (high blood pressure during pregnancy). Some women, however, develop HELLP syndrome without showing signs of these conditions
More technical information : BMC Pregnancy & Childbirth
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