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Wikenigma - an Encyclopedia of Unknowns Wikenigma - an Encyclopedia of the Unknown

Good's syndrome

Good's Syndrome was first described in 1955. Patients develop a thymoma (tumour of the thymus) and have greatly reduced antibody efficiency.

It's a rare disease, but nevertheless affects several thousand people worldwide each year.

The cause is unknown. and the exact criteria for diagnosing the syndrome have still not been formally agreed.

Fifty-five years after Dr. Good’s original observations on thymoma and hypogammaglobulinemia, the pathogenesis of this primary immunodeficiency syndrome remains incompletely understood.

See : Good’s syndrome remains a mystery after 55 years: A systematic review of the scientific evidence Clinical Immunology, 2010 Jun; 135(3): 347–363.


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