User Tools

    To create and edit articles, please register and log-in

Main Menu : categories & index etc.

Main menu
Click categories to expand


A-Z listingplugin-autotooltip__plain plugin-autotooltip_bigA-Z listing

This is an alphabetical index of all content pages.


Other categories

Utilities

Contact
Register
Sandbox

Also see

Importance Ratings
News
Legal
Donate/Sponsor
Curator's rationale
AI Policy



Twitter feed đť•Ź



Feeds + s.e.o. etc.
rss / xml feed
sitemap file
A-Z listing (archived)


Indexed under : Medicine / Diseases / G - L

Wikenigma - an Encyclopedia of Unknowns Wikenigma - an Encyclopedia of the Unknown

Glaucoma

Glaucoma is a group of eye diseases - the leading cause of non-reversible blindness worldwide. It's linked* with increased intra-ocular pressure (IOP) and results in damage to the retinal cells and the optic nerve. (Note the increased IOP is also sometimes called occular hypertension.)

Glaucoma is characterized by a continuous loss of retinal ganglion cells. The cause of glaucoma is associated with an increase in intraocular pressure (IOP), but the underlying pathophysiology is diverse and, in most cases, unknown.

Source : Pharmacology & Therapeutics, April 2023 (early view)

Although the cause in predominantly unknown, it's been found that genetics, environmental factors, and especially age, make it considerably more likely for individuals to develop the disease.

* Important Note : Only about 50% of people with chronic simple glaucoma actually have elevated IOP (ref.)

Results confirmed that IOP is an important factor in glaucoma, but did not support the traditional distinction between “normal” and “elevated” pressure, nor its corollaries, “low-tension” glaucoma and “high-tension” glaucoma.

[link above]

Two of the first-line drugs used to treat high IOP have 'mechanisms of action' which are unexplained. See Bimatoprostplugin-autotooltip__plain plugin-autotooltip_bigBimatoprost

Bimatoprost is a drug used to treat Glaucoma - linked to excess pressure within the eye. It currently has more than 2 million prescriptions per year in the US alone. Marketed, usually as eye-drops, under the brand names Lumigan, Latisse, Vistitan
and Betaxololplugin-autotooltip__plain plugin-autotooltip_bigBetaxolol

Betaxolol - currently sold under brand names Betoptic, Betoptic S, Lokren, Kerlone and others - is a prescription drug used to treat Glaucomaand its associated ocular hypertension. It was patented in 1975 and was first licenced for medical use over forty year…


    Please share this page to help promote Wikenigma !

Dear reader : Do you have any suggestions for the site's content?

Ideas for new topics, and suggested additions / corrections for older ones, are always welcome.

If you have skills or interests in a particular field, and have suggestions for Wikenigma, get in touch !


Or, if you'd like to become a regular contributor . . . request a login password. Registered users can edit the entire content of the site, and also create new pages.

( The 'Notes for contributors' section in the main menu has further information and guidelines etc.)

Automatic Translation

You are currently viewing an auto-translated version of Wikenigma

Please be aware that no automatic translation engines are 100% accurate, and so the auto-translated content will very probably feature errors and omissions.

Nevertheless, Wikenigma hopes that the translated content will help to attract a wider global audience.

Show another (random) article

Further resources :

DOKUWIKI IMPLEMENTATION DESIGN BY UNIV.ORG.UK NOVEMBER 2023