“Calorie restriction, or caloric restriction, or energy restriction, is a dietary regimen that reduces calorie intake without incurring malnutrition or a reduction in essential nutrients. 'Low' can be defined relative to the subject's previous intake before intentionally restricting calories, or relative to an average person of similar body type. In a number of species, including yeast, fish, rodents and dogs, calorie restriction without malnutrition has been shown to slow the biological aging process, resulting in longer maintenance of youthful health and an increase in both median and maximum lifespan.”
Detailed experimental research on caloric restriction's apparent abilty to slow the ageing process has been going on for over 70 years, but “the mechanism underlying this phenomenon is still unknown.” Source: Caloric Restriction and Aging: Studies in Mice and Monkeys
Theories regarding possible mechanisms include the effects of: • reduced core body temperature • reduced cellular divisions • lower metabolic rates • reduced production of free radicals • reduced DNA damage • hormesis (any process in a cell or organism that exhibits a biphasic response to exposure to increasing amounts of a substance or condition)
Ideas for new topics, and suggested additions / corrections for old ones, are always welcome.
If you have skills or interests in a particular field, and have suggestions for Wikenigma, get in touch !
Or, if you'd like to become a regular contributor . . . request a login password. Registered users can edit the entire content of the site, and also create new pages.
( The 'Notes for contributors' section in the main menu has further information and guidelines etc.)