User Tools

    To create and edit articles, please register and log-in

Main Menu

Main menu
Click categories to expand


A-Z listingplugin-autotooltip__plain plugin-autotooltip_bigA-Z listing

This is an alphabetical index of all content pages.


Other categories

Utilities

Contact
Register

Also see

Importance Ratings
News
Legal
Donate/Sponsor
Curator's rationale


Wikenigma supports:


Feeds etc
rss / xml feed
sitemap file
A-Z listing (archived)


Auto-Translate Site
Indexed under : Life Sciences / Genetics

Wikenigma - an Encyclopedia of Unknowns Wikenigma - an Encyclopedia of the Unknown

Oncogenes

Several hundred oncogenes - genes which which have to potential to increase the risk of cancer - have now been identified. The way(s) in which they do so is as yet unknown.

A fundamental aim of cancer research is to identify the molecular changes that cause normal cells to evolve into malignant tumors. Malignant transformation has been proposed to occur as a consequence of the accumulation of genomic aberrations that successively overcome the cellular barriers to malignancy. Although a concerted effort has been made to discover the complement of molecular aberrations required for malignant transformation, the spectrum of events that must occur in a single cell, including which oncogene activation and tumor suppressor gene inactivation events can cooperate to induce malignant transformation, has remained elusive.“
See: Are oncogenes sufficient to cause human cancer? in PNAS November, 2010.


    Share this page :

Dear reader : Do you have any suggestions for the site's content?

Ideas for new topics, and suggested additions / corrections for old ones, are always welcome.

If you have skills or interests in a particular field, and have suggestions for Wikenigma, get in touch !


Or, if you'd like to become a regular contributor . . . request a login password. Registered users can edit the entire content of the site, and also create new pages.

( The 'Notes for contributors' section in the main menu has further information and guidelines etc.)

Automatic Translation

You are currently viewing an auto-translated version of Wikenigma

Please be aware that no automatic translation engines are 100% accurate, and so the auto-translated content will very probably feature errors and omissions.

Nevertheless, Wikenigma hopes that the translated content will help to attract a wider global audience.

Show another (random) article

DOKUWIKI IMPLEMENTATION DESIGN BY UNIV.ORG.UK JULY 2022