Sarcopenia, the decline in skeletal muscle mass and function without any underlying disease, is a major contributor to physical disability, poor quality of life, and death among the elderly […] 40%–50% of individuals over 80 years of age suffer from this loss of muscle mass and function […] The molecular mechanisms responsible for this age‐related condition remain unknown.
Source: Aging Cell, Volume 19, Issue 10
Despite its widespread prevalence (there are currently more than 50 million sufferers worldwide) , the syndrome was only named in 1989,
Many causes have been proposed (genetic, environmental, systemic etc ) but it's now thought that it's likely to be the result of multiple, as yet unidentified, interacting factors.
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