====== Non-celiac gluten sensitivity (NCGS) ======

Non-celiac gluten sensitivity (NCGS) is currently defined as :// "a clinical entity induced by the ingestion of gluten leading to intestinal and/or extraintestinal symptoms that improve once the gluten-containing foodstuff is removed from the diet, and celiac disease and wheat allergy have been excluded".//

It was first described in 1976. Some studies estimate it to be the most common form of the gluten-related disorders - with incidence rates of up to 13% of the (Western) population.

The cause is unknown - though there is speculation that it's an immune-system malfunction of some kind. Some research groups maintain that there is not enough evidence to class NCGS as a distinct clinical disorder.

>Currently there is an absence of any reliable biomarkers, therefore, NCGS remains a diagnosis of exclusion."
>
>\\ See : [[https://onlinelibrary.wiley.com/doi/10.1111/apt.13155|Systematic review: noncoeliac gluten sensitivity]]  //Alimentary Pharmacology & Therapeutics//,  Volume 41, Issue 9 p. 807-820 {{:oa_padlock_grn.png?16&nolink|Open Access}}

----

Also see : [[content:medicine:diseases:g-l:ibs]]