====== Cell size ======

A detailed explanation of the factors which regulate cell size (i.e. the size to which cells grow) has not yet been found. Since (most) cells stop growing when they reach a specific size, it's suggested that there must be some feedback mechanism to restrict growth beyond that point.

>The existence of a “size control” is well known and the control has been studied for a long time, but it has been remarkably resistant to molecular analysis. The attainment of a critical size triggers the periodic events of the cycle such as the S period and mitosis. This control acts as a homeostatic effector that maintains a constant “average” cell size at division through successive cycles in a growing culture. It is a vital link coordinating cell growth with periodic events of the cycle. A size control is present in all the systems and appears to operate near the start of S or of mitosis when the cell has reached a critical size, but __the molecular mechanism by which size is measured remains both obscure and a challenge__." \\ \\ Source : [[https://www.sciencedirect.com/science/article/abs/pii/S0074769603010040?via%3Dihub|Growth dung the cell cycle]]// //(paywalled)//International Review of Cytology, Volume 226, 2003, Pages 165-258//

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Also see : [[content:life_sciences:life_itself:cell_proliferation]]

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