====== Cieplak effect ====== In organic chemistry, the //Cieplak effect //refers to a proposal (from Andrzej Stanislaw Cieplak in 1980) to try to explain why nucleophiles (organic chemicals that donate an electron pair to form a chemical bond) preferentially add to one face of a carbonyl group over another. These types of reactions have been called 'Stereo-selective', and are regularly observed. Technical details, see [[https://en.wikipedia.org/wiki/Cieplak_effect#Criticisms|Wikipedia]] A significant proportion of theorists dispute Cieplak's theory, and various other alternatives have been proposed. Also see [[https://en.wikipedia.org/wiki/Cieplak_effect#Alternative_explanations|Wikipedia]]