User Tools

    Please register ( or log-in ) to create and edit pages
  • Register

Site Tools


Main Menu

Main menu
[ Click categories to expand ]

Other categories

For tests only


Also see:

Content Guidelines
Registration
How to edit pages
Faq
News
Contacts
Legal


444 unknowns listed

Wikenigma supports:


rss / xml feed
sitemap file

Wikenigma - an Encyclopedia of Unknowns Wikenigma - an Encyclopedia of the Unknown Wikenigma - an Encyclopaedia of Unknowns Wikenigma - an Encyclopaedia of the Unknown

Lamotrigine

Lamotrigine is used as an anticonvulsant and mood stabilizer. Currently prescribed in cases of epilepsy, Lennox–Gastaut syndrome and bipolar disorder. Its active biochemical pathways are not known.
more info at Wikipedia

“The action mechanisms underlying the mood-stabilizing effects of lamotrigine are unknown at present but recent studies have produced interesting leads. Lamotrigine modulates various ion channels, altering neuronal excitability. The use-dependent inhibition of neuronal firing by lamotrigine is potentially important because it could result in attenuating supranormal neuronal activities that are possibly associated with bipolar disorder. Lamotrigine inhibits the release of glutamate, similarly to lithium, and its possible association with mood-stabilizing or antidepressant effects needs to be further examined.” see The current understanding of lamotrigine as a mood stabilizer. J Clin Psychiatry. 2004 Jun;65(6):791-804.

Note that Lithium (treatment for bipolar disorder), mentioned above, also works by an as yet unknown mechanism.


DOKUWIKI IMPLEMENTATION DESIGN BY UNIV.ORG.UK