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Content Guidelinesplugin-autotooltip__plain plugin-autotooltip_bigContent guidelines

Ideas for new topics are always welcomed, from experts and non-experts alike - if you're not sure if they'll be accepted by other editors, put them in the 'proposed_content' section for approval. The easiest way to create a new page is to use the

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• Aug 2020 : Currently (beta) testing the new 'WYSIWYG' (What You See Is What You Get) page editor. It greatly simplifies the editing process, avoiding the need to learn the Wiki syntax. (Note: it's currently not 100% stable)

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500 unknowns listed

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Exosomes

Exosomes (a.k.a. extracellular vesicles - EVs) are small protected packets of extracellular RNA that are produced on the cell membrane of most eukaryotic cells. They can separate from the cell wall and travel freely in any bodily fluid. They have been found in every (mammalian) fluid tested to date. They are currently the subject of intense research because they are believed to operate as 'messengers' between body cells. Because they contain genetic information form the cell which produces them, it's thought that they may a be useful marker for detecting diseased cells - remotely from the disease site (in cancer etc).

The following types of RNA have been so far detected outside cells.

Messenger RNA (mRNA)
Transfer RNA (tRNA)
MicroRNA (miRNA)
Small interfering RNA (siRNA)
Long non-coding RNA (lncRNA)

It's not currently known the extent (and mechanisms) to which cells can 'communicate' by this exchange of genetic material.

See: Wikipedia

Also see: The International Society For Extracellular Vesicles

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